A study conducted by Olga Glinskii and her associate leads her to advise extreme caution in HRT use.
The vascular system depends on estrogen for maintenance. When the body decreases its estrogen production, as in after the menopause, the body is unable to regulate blood vessels like it did before.
This might explain why women lose the protection they get from certain conditions such as heart disease and stroke after menopause," said Olga Glinskii, research assistant professor of medical pharmacology and physiology in MU’s School of Medicine and lead author of the study.
She says, “because the body eventually will naturally adapt to the loss of estrogen, we advise extreme caution when using estrogen-based therapy in postmenopausal women.”
"Eventually, the body starts to recognize that it needs blood vessels and starts to adapt through natural responses.
If we start adding estrogen to a system that is learning to adapt without it, we upset this transition process.
What happens to the vascular system during menopause is complex on many different levels, and we do not know enough to determine the best way to use hormone therapy."
After a period of deterioration, the body learns to adapt to the estrogen loss and eventually maintains the system in a different way.
No comments:
Post a Comment